643 Grand AVE South San Francisco, CA 94080 Open Sat 1PM-4PM

UPDATED: 08/28/2026 06:35 AM ON SITE: New on site today

$1,248,000

3 Beds4 Baths1,630 SqFt

Key Details

Property Type Single Family Home

Sub Type Single Family Home

Listing Status Active

Purchase Type For Sale

Square Footage 1,630 sqft

Price per Sqft $765

MLS Listing ID ML82059314

Bedrooms 3

Full Baths 4

Year Built 1895

Lot Size 3,500 Sqft

Property Sub-Type Single Family Home

Location

State CA

County San Mateo

Area Old South Sf / Rocca

Zoning RM0000

Rooms

Family Room No Family Room

Dining Room Dining Area in Living Room

Interior

Heating Central Forced Air

Cooling None

Exterior

Parking Features Detached Garage,On Street

Garage Spaces 2.0

Utilities Available Public Utilities

Roof Type Shingle

Building

Story 2

Foundation Concrete Slab

Sewer Sewer - Public

Water Public,Water Softener - Owned

Level or Stories 2

Others

Tax ID 012-241-120

Miscellaneous Skylight,Walk-in Closet

Horse Property No

Special Listing Condition Not Applicable

Property Description

Ideally located near Downtown South San Francisco and the cities thriving biotech and life-sciences corridor, 643 Grand Avenue where space, comfort, and a remarkable garden setting come together in the heart of South San Francisco. 643 Grand Avenue offers a spacious and versatile layout with excellent access to major transportation and employment centers. The home features 3 bedrooms and 4 bathrooms, with a private full bathroom for each bedroom. Additional highlights include high ceilings, abundant natural light, hardwood floors, a full basement with ample storage, and a detached 2-car garage equipped with a 220-volt outlet for EV charging. The home also features a water purification system, tankless water heater, and water softener. The quaint lot includes a freshly manicured organic vegetable garden with sunflowers and offers potential for an ADU. Conveniently located near Downtown South San Francisco, Genentech, Caltrain, US-101, and I-280.

Based on information from the MLSListings MLS as of 08/28/2026 08:00
All data, including all measurements and calculations of area, is obtained from various sources and has not been, and will not be, verified by broker or MLS. All information should be independently reviewed and verified for accuracy. Properties may or may not be listed by the office/agent presenting the information. The data relating to real estate for sale on this display comes in part from the Internet Data Exchange program of the MLSListings Inc. MLS system. Real estate listings held by brokerage firms other than Blok are marked with the Internet Data Exchange and detailed information about them includes the names of the listing brokers and listing agents.

Copyright 2026 MLSListings Inc All rights reserved. The broker providing this data believes the data to be correct, but advises interested parties to confirm all information before relying on it for a purchase decision. The information being provided is for consumers' personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. Data last updated at 08/28/2026 08:00
The data relating to real estate for sale on this display comes in part from the Internet Data Exchange program of the MLSListings Inc. MLS system. Real estate listings held by brokerage firms other than Blok are marked with the Internet Data Exchange and detailed information about them includes the names of the listing brokers and listing agents.